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Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is liver hepatocellular carcinoma.
TNS4 links the focal adhesion and cell adhesion signaling to the actin cytoskeleton. It may be involved in cell survival and migration. The protein may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton and promote apoptosis, via its cleavage by caspase-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C terminal tensin like; c-ten; C-terminal tensin-like protein; Tensin-4
基因别名: CTEN; PP14434; TNS4
UniProt ID: (Human) Q8IZW8
Entrez Gene ID: (Human) 84951
分子生物学功能: non-motor actin binding protein