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Invitrogen
Thimet Oligopeptidase Polyclonal Antibody
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Thimet Oligopeptidase Antibody (PA5-30229) in WB
Western Blot using Thimet Oligopeptidase Polyclonal Antibody (Product # PA5-30229). Sample (30 µg of whole cell lysate). Lane A: A549. Lane B: HCT116. 7.5% SDS PAGE. Thimet Oligopeptidase Polyclonal Antibody (Product # PA5-30229) diluted at 1:1,000.
产品信息
PA5-30229
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human Thimet Oligopeptidase. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.88 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A549, HeLa, HepG2, HCT116, mouse brain.
Predicted reactivity: Mouse (92%), Rat (91%), Zebrafish (82%), Pig (94%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.24; EC 3.4.24.15; Endopeptidase 24.15; MP78; Thimet oligopeptidase
基因别名: AI131655; AI327041; EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888, (Mouse) Q8C1A5
Entrez Gene ID: (Human) 7064, (Mouse) 50492
