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Proteintech
UBA6 Polyclonal Antibody
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产品信息
13211-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBA6 Fusion Protein Ag4000 (87-389 aa encoded by BC031637)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody recognizes the full-length (118 kDa) and the truncated isoform CRA_b (60-70 kDa) of UBA6 (NCBI).
Immunogen sequence: AVTIHDTEK CQAWDLGTNF FLSEDDVVNK RNRAEAVLKH IAELNPYVHV TSSSVPFNET TDLSFLDKYQ CVVLTEMKLP LQKKINDFCR SQCPPIKFIS ADVHGIWSRL FCDFGDEFEV LDTTGEEPKE IFISNITQAN PGIVTCLENH PHKLETGQFL TFREINGMTG LNGSIQQITV ISPFSFSIGD TTELEPYLHG GIAVQVKTPK TVFFESLERQ LKHPKCLIVD FSNPEAPLEI HTAMLALDQF QEKYSRKPNV GCQQDSEELL KLATSISETL EEKVTIEIYG CPNICLLIHK CSVY (87-389 aa encoded by BC031637)
靶标信息
UBA6 (UBE1L2, MOP-4) is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family. It is a part of the cascade to attach ubiquitin (Ub) covalently to substrate proteins. UBA6 activates ubiquitin by first adenylating its carboxy-terminal glycine residue with ATP and then linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Its isoforms influence spermatogenesis and male fertility. UBA6 is highly expressed in human monocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E1-L2; Monocyte protein 4; MOP-4; UBA6, ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme 6; ubiquitin-activating enzyme E1-like 2; Ubiquitin-activating enzyme E1-like protein 2; ubiquitin-like modifier activating enzyme 6; Ubiquitin-like modifier-activating enzyme 6
基因别名: 4930542H01; 5730469D23Rik; AU021846; AW124799; E1-L2; MOP-4; MOP4; UBA6; UBE1L2
UniProt ID: (Human) A0AVT1, (Mouse) Q8C7R4
Entrez Gene ID: (Human) 55236, (Mouse) 231380
