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Invitrogen
UBE2A Polyclonal Antibody
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UBE2A Antibody (PA5-27186) in ICC/IF
UBE2A Polyclonal Antibody detects UBE2A protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A375 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: UBE2A protein stained by UBE2A Polyclonal Antibody (Product # PA5-27186) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-27186
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length human UBE2A Recombinant protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (100%), Rat (93%), Zebrafish (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2 ubiquitin-conjugating enzyme A; HR6A; RAD6 homolog A; Ubiquitin carrier protein A; ubiquitin conjugating enzyme E2A; Ubiquitin-conjugating enzyme E2 A; Ubiquitin-protein ligase A
基因别名: HHR6A; MRXS30; MRXSN; RAD6A; UBC2; UBE2A
UniProt ID: (Human) P49459
Entrez Gene ID: (Human) 7319
protein polyubiquitination
in utero embryonic development
DNA repair
postreplication repair
ubiquitin-dependent protein catabolic process
positive regulation of cell proliferation
response to UV
histone H2A ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
maternal process involved in female pregnancy
protein K48-linked ubiquitination
protein K11-linked ubiquitination
