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Proteintech
UBE3C Polyclonal Antibody
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产品信息
12333-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBE3C Fusion Protein Ag2966 (1-350 aa encoded by BC026241)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MFSFEGDFK TRPKVSLGGA SRKYSIQRSA FDRCATLSQS GGAFPIANGP NLTLLVRQLL FFYKQNEDSK RLIWLYQNLI KHSSLFVKQL DGSERLTCLF QIKRLMSLCC RLLQNCNDDS LNVALPMRML EVFSSENTYL PVLQDASYVV SVIEQILHYM IHNGYYRSLY LLINSKLPSS IEYSDLSRVP IAKILLENVL KPLHFTYNSC PEGARQQVFT AFTEEFLAAP FTDQIFHFII PALADAQTVF PYEPFLNALL LIESRCSRKS GGAPWLFYFV LTVGENYLGA LSEEGLLVYL RVLQTFLSQL PVSPASASCH DSASDSEEES EEADKPSSPE DGRLSVSYIT E (1-350 aa encoded by BC026241)
靶标信息
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HECT-type ubiquitin transferase E3C; HectH2; Homologous to E6AP carboxyl terminus homologous protein 2; RAUL; RTA-associated ubiquitin ligase; ubiquitin protein ligase E3C; ubiquitin-protein isopeptide ligase (E3); Ubiquitin-protein ligase E3C
基因别名: AI853514; HECTH2; KIAA0010; KIAA10; mKIAA0010; RGD1559986; UBE3C
UniProt ID: (Human) A4D235, (Mouse) Q80U95
Entrez Gene ID: (Human) 9690, (Rat) 362294, (Mouse) 100763
ubiquitin-protein transferase activity
protein binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
