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Proteintech
UBE4A Polyclonal Antibody
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产品信息
21548-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBE4A Fusion Protein Ag16211 (717-1066 aa encoded by BC112367)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: QLAEALIKV FVDIEFTGDP HQFEQKFNYR RPMYPILRYM WGTDTYRESI KDLADYASKN LEAMNPPLFL RFLNLLMNDA IFLLDEAIQY LSKIKIQQIE KDRGEWDSLT PEARREKEAG LQMFGQLARF HNIMSNETIG TLAFLTSEIK SLFVHPFLAE RIISMLNYFL QHLVGPKMGA LKVKDFSEFD FKPQQLVSDI CTIYLNLGDE ENFCATVPKD GRSYSPTLFA QTVRVLKKIN KPGNMIMAFS NLAERIKSLA DLQQQEEETY ADACDEFLDP IMSTLMCDPV VLPSSRVTVD RSTIARHLLS DQTDPFNRSP LTMDQIRPNT ELKEKIQRWL AERKQQKEQL E (717-1066 aa encoded by BC112367)
靶标信息
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: RING-type E3 ubiquitin transferase E4 A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog
基因别名: 4732444G18Rik; 9930123J21Rik; E4; KIAA0126; UBE4A; UBOX2; UFD2; UFD2b
UniProt ID: (Human) Q14139, (Mouse) E9Q735
Entrez Gene ID: (Human) 9354, (Mouse) 140630
protein binding
ligase activity
ubiquitin-ubiquitin ligase activity
ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
