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Proteintech
UBE4B Polyclonal Antibody
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产品信息
18148-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBE4B Fusion Protein Ag12836 (825-1173 aa encoded by BC093696)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EMIENHPLS TKLLVPSLMK FYTDVEHTGA TSEFYDKFTI RYHISTIFKS LWQNIAHHGT FMEEFNSGKQ FVRYINMLIN DTTFLLDESL ESLKRIHEVQ EEMKNKEQWD QLPRDQQQAR QSQLAQDERV SRSYLALATE TVDMFHILTK QVQKPFLRPE LGPRLAAMLN FNLQQLCGPK CRDLKVENPE KYGFEPKKLL DQLTDIYLQL DCARFAKAIA DDQRSYSKEL FEEVISKMRK AGIKSTIAIE KFKLLAEKVE EIVAKNARAE IDYSDAPDEF RDPLMDTLMT DPVRLPSGTI MDRSIILRHL LNSPTDPFNR QTLTESMLEP VPELKEQIQA WMREKQNSDH (825-1173 aa encoded by BC093696)
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homologous to yeast UFD2; Homozygously deleted in neuroblastoma 1; homozygously deleted in neuroblastoma-1; RING-type E3 ubiquitin transferase E4 B; Ubiquitin conjugation factor E4 B; Ubiquitin fusion degradation protein 2; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (homologous to yeast UFD2); ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitination factor E4B, UFD2 homolog; UFD2A-III/UBE4B-III splice isoform
基因别名: 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; E4; HDNB1; KIAA0684; mKIAA0684; UBE4B; UBOX3; UFD2; UFD2A; Ufd2p
UniProt ID: (Human) O95155, (Mouse) Q9ES00
Entrez Gene ID: (Human) 10277, (Mouse) 63958, (Rat) 298652
protein polyubiquitination
ventricular trabecula myocardium morphogenesis
protein monoubiquitination
granzyme-mediated apoptotic signaling pathway
response to UV
neuron projection development
response to endoplasmic reticulum stress
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein autoubiquitination
ubiquitin-dependent protein catabolic process
protein ubiquitination
cellular protein catabolic process
