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Abnova
UBE4B Monoclonal Antibody (8F9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010277-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
8F9
抗原
UBE4B (NP_006039, 1075 a.a. approximately 1173 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: FKLLAEKVEE IVAKNARAEI DYSDAPDEFR DPLMDTLMTD PVRLPSGTIM DRSIILRHLL NSPTDPFNRQ TLTESMLEPV PELKEQIQAW MREKQNSDH
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; RING-type E3 ubiquitin transferase E4 B; similar to Saccharomyces cerevisiae Ufd2p; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (UFD2 homolog, yeast); UFD2; Ufd2a/Ube4B; ubiquitin ligase E3 and E4 activity; alternative splice form specific for striated muscle cells; unnamed protein product
基因别名: E4; HDNB1; UBOX3; UFD2; UFD2A
UniProt ID: (Human) O95155
Entrez Gene ID: (Human) 10277
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
