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Invitrogen
UBP1 Polyclonal Antibody
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产品信息
PA5-50696
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human upstream binding protein 1
偶联物
形式
Liquid
浓度
2.7 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total UBP1 protein.
靶标信息
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NF2d9; Nuclear factor 2d9; Transcription factor LBP-1; Upstream-binding protein 1
基因别名: Cp2b; LBP-1a; LBP-1B; LBP1; LBP1A; LBP1B; NF2d9; UBP1
UniProt ID: (Human) Q9NZI7, (Mouse) Q811S7
Entrez Gene ID: (Human) 7342, (Mouse) 22221
