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Proteintech
UBXN2B Polyclonal Antibody
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产品信息
25141-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBXN2B fusion protein Ag18259
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: MAEGGGPEPG EQERRSSGPR PPSARDLQLA LAELYEDEVK CKSSKSNRPK ATVFKSPRTP PQRFYSSEHE YSGLNIVRPS TGKIVNELFK EAREHGAVPL NEATRASGDD KSKSFTGGGY RLGSSFCKRS EYIYGENQLQ DVQILLKLWS NGFSLDDGEL RPYNEPTNAQ
靶标信息
UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NSFL1 cofactor p37; p97 cofactor p37; UBX domain-containing protein 2B
基因别名: 3110003A22Rik; 6430407D20Rik; AI451665; p37; UBXN2B
UniProt ID: (Human) Q14CS0, (Mouse) Q0KL01
Entrez Gene ID: (Human) 137886, (Mouse) 68053
