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Proteintech
UMPS Polyclonal Antibody
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产品信息
14830-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UMPS Fusion Protein Ag6620 (189-480 aa encoded by BC000364)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VDAETVGRV KRFIQENVFV AANHNGSPLS IKEAPKELSF GARAELPRIH PVASKLLRLM QKKETNLCLS ADVSLARELL QLADALGPSI CMLKTHVDIL NDFTLDVMKE LITLAKCHEF LIFEDRKFAD IGNTVKKQYE GGIFKIASWA DLVNAHVVPG SGVVKGLQEV GLPLHRGCLL IAEMSSTGSL ATGDYTRAAV RMAEEHSEFV VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII IVGRGIISAA DRLEAAEMYR KAAWEAYLSR LGV (189-480 aa encoded by BC000364)
靶标信息
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: OMPdecase; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-phosphate decarboxylase; UMP synthase; Uridine 5'-monophosphate synthase
基因别名: 1700095D23Rik; AA408257; AL033308; BB164745; OK/SW-cl.21; OPRT; UMPS
UniProt ID: (Human) P11172, (Mouse) P13439
Entrez Gene ID: (Human) 7372, (Mouse) 22247
