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Invitrogen
UNC13A Polyclonal Antibody
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产品信息
PA5-59563
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human UNC13A
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: QLSEDFDPDE HSLQGSDMED ERDRDSYHSC HSSVSYHKDS PRWDQDEEEL EEDLEDFLEE EE
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 39%.
靶标信息
UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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