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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin -like domains and 2 type I thrombospondin motifs in the extracellular region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: Netrin receptor UNC5C; Protein unc-5 homolog 3; Protein unc-5 homolog C; Rostral cerebellar malformation protein; UNC-5 homolog 3; unc-5 homolog C; unc5 (C.elegans homolog) c; unc5 homolog 3
Gene Aliases: B130051O18Rik; Rcm; UNC5C; UNC5H3
UniProt ID: (Human) O95185, (Mouse) O08747, (Rat) Q761X5
Entrez Gene ID: (Human) 8633, (Mouse) 22253, (Rat) 362049
Molecular Function:
transmembrane signal receptor
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