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Invitrogen
UNC5D Polyclonal Antibody
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产品信息
PA5-60168
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human UNC5D
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: TFNFKTVRQG NSLLLNSAMQ PDLTVSRTYS GPICLQDPLD KELMTESSLF NPLSDIKVKV QSSFMVSLGV SERAEYHGKN HSRTFPHGNN HSFSTMHPRN KMPYIQNLSS LPTRTELRTT GVFGHLGGRL VMPNTGVSL
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
靶标信息
UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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