应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫细胞化学 (ICC/IF) |
1:50 - 1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-367 of human UROD. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.81 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808148 |
Immunogen sequence: MEANGLGPQG FPELKNDTFL RAAWGEETDY TPVWCMRQAG RYLPEFRETR AAQDFFSTCR SPEACCELTL QPLRRFPLDA AIIFSDILVV PQALGMEVTM VPGKGPSFPE PLREEQDLER LRDPEVVASE LGYVFQAITL TRQRLAGRVP LIGFAGAPWT LMTYMVEGGG SSTMAQAKRW LYQRPQASHQ LLRILTDALV PYLVGQVVAG AQALQLFESH AGHLGPQLFN KFALPYIRDV AKQVKARLRE AGLAPVPMII FAKDGHFALE ELAQAGYEVV GLDWTVAPKK ARECVGKTVT LQGNLDPCAL YASEEEIGQL VKQMLDDFGP HRYIANLGHG LYPDMDPEHV GAFVDAVHKH SRLLRQN; Positive Samples: SW620, K-562, SW480, Mouse liver, Mouse kidney, Mouse testis, Mouse heart, HepG2; Cellular Location: Cytoplasm
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: UPD; URO D; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
基因别名: AI323803; PCT; UPD; Uro-d; UROD
UniProt ID: (Human) P06132, (Mouse) P70697
Entrez Gene ID: (Human) 7389, (Mouse) 22275
分子生物学功能:
methyltransferase