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Proteintech
USF1 Polyclonal Antibody
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产品信息
22327-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
USF1 Fusion Protein Ag17789 (1-310 aa encoded by BC035505)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKGQQKTAE TEEGTVQIQE GAVATGEDPT SVAIASIQSA ATFPDPNVKY VFRTENGGQV MYRVIQVSEG QLDGQTEGTG AISGYPATQS MTQAVIQGAF TSDDAVDTEG TAAETHYTYF PSTAVGDGAG GTTSGSTAAV VTTQGSEALL GQATPPGTGQ FFVMMSPQEV LQGGSQRSIA PRTHPYSPKS EAPRTTRDEK RRAQHNEVER RRRDKINNWI VQLSKIIPDC SMESTKSGQS KGGILSKACD YIQELRQSNH RLSEELQGLD QLQLDNDVLR QQVEDLKNKN LLLRAQLRHH GLEVVIKNDS N (1-310 aa encoded by BC035505)
靶标信息
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: bHLHb11; Class B basic helix-loop-helix protein 11; Major late transcription factor 1; Upstream stimulatory factor 1; usf1-bd
基因别名: BHLHB11; FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; USF; USF1
UniProt ID: (Human) P22415
Entrez Gene ID: (Human) 7391
double-stranded DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
enzyme binding
protein kinase binding
protein homodimerization activity
histone deacetylase binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
regulation of transcription from RNA polymerase II promoter by glucose
positive regulation of transcription from RNA polymerase II promoter by glucose
response to hypoxia
glucose metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to UV
late viral transcription
cellular response to insulin stimulus
glucose homeostasis
positive regulation of transcription from RNA polymerase II promoter
carbon catabolite regulation of transcription
negative regulation of fibrinolysis
lipid homeostasis
