Abnova

USP16 Polyclonal Antibody, MaxPab™

Name: USP16 Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00010600-B01P

查看其他9个USP16抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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USP16 Antibody (H00010600-B01P) in WB

Western Blot analysis of USP16 expression in transfected 293T cell line by USP16 MaxPab polyclonal antibody. Lane 1: USP16 transfected lysate(90.42 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00010600-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

10-100 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

USP16 (AAH30777.1, 1 a.a. approximately 822 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MGKKRTKGKT VPIDDSSETL EPVCRHIRKG LEQGNLKKAL VNVEWNICQD CKTDNKVKDK AEEETEEKPS VWLCLKCGHQ GCGRNSQEQH ALKHYLTPRS EPHCLVLSLD NWSVWCYVCD NEVQYCSSNQ LGQVVDYVRK HASITTPKPE KDNGNIELEN KKLEKESKNE QEREKKENMA KENPPMNSPC QITVKGLSNL GNTCFFNAVM QNLSQTPVLR ELLKEVKMSG TIVKIEPPDL ALTEPLEINL EPPGPLTLAM SQFLNEMQET KKGVVTPKEL FSQVCKKAVR FKGYQQQDSQ ELLRYLLDGM RAEEHQRVSK GILKAFGNST EKLDEELKNK VKDYEKKKSM PSFVDRIFGG ELTSMIMCDQ CRTVSLVHES FLDLSLPVLD DQSGKKSVND KNLKKTVEDE DQDSEEEKDN DSYIKERSDI PSGTSKHLQK KAKKQAKKQA KNQRRQQKIQ GKVLHLNDIC TIDHPEDSDN EAEMSLQGEV NIKSNHISQE GVMHKEYCVN QKDLNGQAKM IESVTDNQKS TEEVDMKNIN MDNDLEVLTS SPTRNLNGAY LTEGSNGEVD ISNGFKNLNL NAALHPDEIN IEILNDSHTP GTKVYEVVNE DPETAFCTLA NREVFNTDEC SIQHCLYQFT RNEKLRDANK LLCEVCTRRQ CNGPKANIKG ERKHVYTNAK KQMLISLAPP VLTLHLKRFQ QAGFNLRKVN KHIKFPEILD LAPFCTLKCK NVAEENTRVL YSLYGVVEHS GTMRSGHYTA YAKARTANSH LSNLVLHGDI PQDFEMESKG QWFHISDTHV QAVPTTKVLN SQAYLLFYER IL

靶标信息

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Deubiquitinating enzyme 16; Ubiquitin carboxyl-terminal hydrolase 16; ubiquitin specific protease 16; Ubiquitin thioesterase 16; ubiquitin thiolesterase 16; Ubiquitin-processing protease UBP-M; ubiquitin-specific processing protease 16; Ubiquitin-specific-processing protease 16; USP16

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基因别名: MSTP039; UBP-M; UBPM; USP16

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UniProt ID: (Human) B3KN13

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Entrez Gene ID: (Human) 10600

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功能

transcription coactivator activity cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity zinc ion binding histone binding ubiquitin binding cysteine protease

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