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Proteintech
USP20 Polyclonal Antibody
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产品信息
17491-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
USP20 Fusion Protein Ag11590 (1-351 aa encoded by BC039593)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGDSRDLCP HLDSIGEVTK EDLLLKSKGT CQSCGVTGPN LWACLQVACP YVGCGESFAD HSTIHAQAKK HNLTVNLTTF RLWCYACEKE VFLEQRLAAP LLGSSSKFSE QDSPPPSHPL KAVPIAVADE GESESEDDDL KPRGLTGMKN LGNSCYMNAA LQALSNCPPL TQFFLECGGL VRTDKKPALC KSYQKLVSEV WHKKRPSYVV PTSLSHGIKL VNPMFRGYAQ QDTQEFLRCL MDQLHEELKE PVVATVALTE ARDSDSSDTD EKREGDRSPS EDEFLSCDSS SDRGEGDGQG RGGGSSQAET ELLIPDEAGR AISEKERMKD RKFSWGQQRT NSEQVDEDAD VD (1-351 aa encoded by BC039593)
靶标信息
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Deubiquitinating enzyme 20; hVDU2; pVHL-interacting deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific protease 20; Ubiquitin thioesterase 20; ubiquitin thiolesterase 20; Ubiquitin-specific-processing protease 20; VHL-interacting deubiquitinating enzyme 2
基因别名: 1700055M05Rik; AI467231; hVDU2; KIAA1003; LSFR3A; USP20; VDU2
UniProt ID: (Human) Q9Y2K6, (Mouse) Q8C6M1
Entrez Gene ID: (Human) 10868, (Mouse) 74270, (Rat) 311856
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
metal ion binding
cysteine protease
ubiquitin-dependent protein catabolic process
endocytosis
regulation of G-protein coupled receptor protein signaling pathway
protein deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
