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Bethyl Laboratories
USP20/VDU2 Polyclonal Antibody
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USP20/VDU2 Antibody (A301-189A) in WB
Detection of mouse USP20/VDU2 by western blot. Samples: Whole cell lysate (50 µg) from NIH 3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. Antibodies: Affinity purified rabbit anti-USP20/VDU2 antibody (Product # A301-189A) (lot A301-189A-2) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A301-189A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 863 and 913 of Human ubiquitin specific peptidase 20 (pVHL-interacting deubiquitinating enzyme 2).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 20; hVDU2; pVHL-interacting deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific protease 20; Ubiquitin thioesterase 20; ubiquitin thiolesterase 20; Ubiquitin-specific-processing protease 20; VHL-interacting deubiquitinating enzyme 2
基因别名: 1700055M05Rik; AI467231; hVDU2; KIAA1003; LSFR3A; USP20; VDU2
UniProt ID: (Human) Q9Y2K6, (Mouse) Q8C6M1
Entrez Gene ID: (Human) 10868, (Mouse) 74270
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
metal ion binding
cysteine protease
ubiquitin-dependent protein catabolic process
endocytosis
regulation of G-protein coupled receptor protein signaling pathway
protein deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
