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Immunogen sequence: MPIVDKLKEA LKPGRKDSAD DGELGKLLAS SAKKVLLQKI EFEPASKSFS YQLEALKSKY VLLNPKTEGA SRHKSGDDPP ARRQGSEHTY ESCGDGVPAP QKVLFPTERL SLRWERVFRV; Positive Samples: U-87MG, A-431, HeLa; Cellular Location: Nucleus, nucleolus
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; ubiquitin thiolesterase 36; Ubiquitin-specific-processing protease 36
基因别名: 2700002L06Rik; DUB1; KIAA1453; mKIAA1453; USP36
UniProt ID: (Human) Q9P275, (Mouse) B1AQJ2
Entrez Gene ID: (Human) 57602, (Mouse) 72344