Abnova

VASN Polyclonal Antibody, MaxPab™

Name: VASN Polyclonal Antibody, MaxPab\u2122
Brand: Abnova
SKU: H00114990-B01P

查看其他16个VASN抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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VASN Antibody (H00114990-B01P) in WB

Western Blot analysis of VASN expression in transfected 293T cell line by VASN MaxPab polyclonal antibody. Lane 1: VASN transfected lysate(74.03 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00114990-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

VASN (AAH68575.1, 1 a.a. approximately 673 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MCSRVPLLLP LLLLLALGPG VQGCPSGCQC SQPQTVFCTA RQGTTVPRDV PPDTVGLYVF ENGITMLDAG SFAGLPGLQL LDLSQNQIAS LPSGVFQPLA NLSNLDLTAN RLHEITNETF RGLRRLERLY LGKNRIRHIQ PGAFDTLDRL LELKLQDNEL RALPPLRLPR LLLLDLSHNS LLALEPGILD TANVEALRLA GLGLQQLDEG LFSRLRNLHD LDVSDNQLER VPPVIRGLRG LTRLRLAGNT RIAQLRPEDL AGLAALQELD VSNLSLQALP GDLSGLFPRL RLLAAARNPF NCVCPLSWFG PWVRESHVTL ASPEETRCHF PPKNAGRLLL ELDYADFGCP ATTTTATVPT TRPVVREPTA LSSSLAPTWL SPTAPATEAP SPPSTAPPTV GPVPQPQDCP PSTCLNGGTC HLGTRHHLAC LCPEGFTGLY CESQMGQGTR PSPTPVTPRP PRSLTLGIEP VSPTSLRVGL QRYLQGSSVQ LRSLRLTYRN LSGPDKRLVT LRLPASLAEY TVTQLRPNAT YSVCVMPLGP GRVPEGEEAC GEAHTPPAVH SNHAPVTQAR EGNLPLLIAP ALAAVLLAAL AAVGAAYCVR RGRAMAAAAQ DKGQVGPGAG PLELEGVKVP LEPGPKATEG GGEALPSGSE CEVPLMGFPG PGLQSPLHAK PYI

靶标信息

The VASN gene encodes the protein vasorin, a type I transmembrane protein involved in cellular signaling, vascular development, and tissue repair. Vasorin is characterized by its expression in various tissues, including vascular endothelial cells and smooth muscle cells, where it functions to modulate cell proliferation and differentiation. It plays a significant role in the regulation of vascular remodeling and homeostasis by interacting with signaling molecules like transforming growth factor-beta (TGF-β), thereby influencing processes such as angiogenesis and wound healing. Vasorin is implicated in inhibiting TGF-β signaling pathways, which are crucial for maintaining vascular integrity and preventing excessive fibrosis during tissue repair. Dysregulation of VASN expression can contribute to pathological conditions, including cardiovascular diseases and cancer, where abnormal vascular remodeling and cell proliferation are evident. Research into vasorin continues to explore its functional mechanisms and potential therapeutic applications in diseases characterized by vascular dysregulation and tissue remodeling.

仅用于科研。不用于诊断过程。未经明确授权不得转售。