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Proteintech
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The antibody is specific to VASP.
Immunogen sequence: MSETVICSS RATVMLYDDG NKRWLPAGTG PQAFSRVQIY HNPTANSFRV VGRKMQPDQQ VVINCAIVRG VKYNQATPNF HQWRDARQVW GLNFGSKEDA AQFAAGMASA LEALEGGGPP PPPALPTWSV PNGPSPEEVE QQKRQQPGPS EHIERRVSNA GGPPAPPAGG PPPPPGPPPP PGPPPPPGLP PSGVPAAAHG AGGGPPPAPP LPAAQGPGGG GAGAPGLAAA IAGAKLRKVS KQEEASGGPT APKAESGRSG GGGLMEEMNA MLARRRKATQ VGEKTPKDES ANQEEPEARV PAQSESVRRP WEKNSTTLPR MKSSSSVTTS ETQPCTPSSS DYSDLQRVKQ ELLEEVKKEL QKVKEEIIEA FVQELRKRGS P (1-380 aa encoded by BC038224)
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Enah/Vasp-like; Vasodilator-stimulated phosphoprotein; VASP
基因别名: VASP
UniProt ID: (Human) P50552, (Mouse) P70460
Entrez Gene ID: (Human) 7408, (Rat) 361517, (Mouse) 22323