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Invitrogen
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PA1-959 detects VDAC3 in mouse, human, rat, rabbit and bovine samples.
PA1-959 has been used successfully in Western blot, ELISA, immunofluorescence, and immunohistochemistry (paraffin) procedures. By Western blot PA1-959 is specific for the ~30 kDa VDAC3 protein.
The PA1-959 immunogen is recombinant, His-tagged VDAC3 protein expressed in E. coli.
The Voltage-Dependent Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。