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This Antibody was verified by Independent antibody to ensure that the antibody binds to the antigen stated.
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other cadherin family members.
VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 7B4 antigen; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144; cd144 antigen; cell-cell adhesion protein; endothelial-specific cadherin; Vascular endothelial cadherin; VE-cadherin
基因别名: 7B4; CD144; CDH5
UniProt ID: (Bovine) Q6URK6, (Human) P33151
Entrez Gene ID: (Bovine) 414735, (Human) 1003
分子生物学功能: cadherin