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Invitrogen
VEGF Receptor 2 Polyclonal Antibody
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产品信息
PA1-21025
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminal region of the human protein.
偶联物
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-21025 detects VEGF Receptor 2 in human, mouse, and rat samples.
PA1-21025 has been successfully used in immunohistochemistry (paraffin) and Western blot procedures.
PA1-21025 immunogen corresponds to synthetic peptide corresponding to the C-terminal region of the human protein.
靶标信息
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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