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Invitrogen
VGAT Polyclonal Antibody
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VGAT Antibody (PA5-111832) in IHC (F)
Immunohistochemical staining of perfusion-fixed frozen rat brain sections with a Polyclonal VGAT antibody(Product # PA5-111832, diluted 1:600), followed by goat anti-guinea pig-AlexaFluor-594. Panel A. VGAT immunoreactivity (red) appears in the granule layer (GL) and in 8220pinceau8221 structures adjacent to purkinje cells (arrows). Panel B. Pre-incubation of the antibody with Vesicular GABA Transporter/VGA... View More
产品信息
PA5-111832
产品规格
宿主/亚型
Guinea pig
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 106-120 of rat vesicular GABA transporter (Cytoplasmic, N-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)GEFGGHD KPKITAWE
Homology: Mouse, human amino acid residues are identical.
靶标信息
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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