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产品信息
PA5-50845
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the C terminal of human vacuole membrane protein 1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.9 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636297 |
产品详细信息
The antibody detects endogenous levels of total VMP1 / TMEM49 protein.
靶标信息
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NF-E2 induceble protein-2; NF-E2-inducible protein 2; Protein ni-2; Transmembrane protein 49; Vacuole membrane protein 1
基因别名: 3110098I04Rik; 4930579A11Rik; AI787464; EPG3; HSPC292; mir-21a; ni-2; TANGO5; TDC1; TMEM49; VMP1
UniProt ID: (Human) Q96GC9, (Rat) Q91ZQ0, (Mouse) Q99KU0
Entrez Gene ID: (Human) 81671, (Rat) 192129, (Mouse) 75909
分子生物学功能:
transmembrane signal receptor
