The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
蛋白别名: 193 kDa vault protein; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; ADP-ribosyltransferase diphtheria toxin-like 4; ARTD4; H5 proline-rich; I-alpha-I-related; PARP-4; PARP-related; PARP-related/IalphaI-related H5/proline-rich; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; Poly [ADP-ribose] polymerase 4; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase-like 1; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; vault protein, 193-kDa; von Willebrand factor A domain containing 5C; VPARP
基因别名: ADPRTL1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; KIAA0177; p193; PARP-4; PARP4; PARPL; PH5P; VAULT3; VPARP; VWA5C
分子生物学功能: protein modifying enzyme