Product References
PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma.
Autophagy
Sarkar C,Jones JW,Hegdekar N,Thayer JA,Kumar A,Faden AI,Kane MA,Lipinski MM
38-2100 was used in Western Blotting to demonstrate that LMP occurs in neurons following controlled cortical impact induced traumatic brain injury in mice, leading to impaired macroautophagy and neuronal cell death.
Sun Mar 01 00:00:00 UTC 2020
Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation.
Journal of neuroinflammation
Ye X,Zhu M,Che X,Wang H,Liang XJ,Wu C,Xue X,Yang J
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Sat Jan 11 00:00:00 UTC 2020
Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells.
Molecular carcinogenesis
Panda PK,Naik PP,Praharaj PP,Meher BR,Gupta PK,Verma RS,Maiti TK,Shanmugam MK,Chinnathambi A,Alharbi SA,Sethi G,Agarwal R,Bhutia SK
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunocytochemistry
Tue May 01 00:00:00 UTC 2018
Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells.
Molecular carcinogenesis
Panda PK,Naik PP,Praharaj PP,Meher BR,Gupta PK,Verma RS,Maiti TK,Shanmugam MK,Chinnathambi A,Alharbi SA,Sethi G,Agarwal R,Bhutia SK
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunocytochemistry
Tue May 01 00:00:00 UTC 2018
Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells.
Molecular carcinogenesis
Panda PK,Naik PP,Praharaj PP,Meher BR,Gupta PK,Verma RS,Maiti TK,Shanmugam MK,Chinnathambi A,Alharbi SA,Sethi G,Agarwal R,Bhutia SK
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunocytochemistry
Tue May 01 00:00:00 UTC 2018
NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex.
Frontiers in cellular and infection microbiology
Aikawa C,Nakajima S,Karimine M,Nozawa T,Minowa-Nozawa A,Toh H,Yamada S,Nakagawa I
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Wed Sep 18 00:00:00 UTC 2019
NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex.
Frontiers in cellular and infection microbiology
Aikawa C,Nakajima S,Karimine M,Nozawa T,Minowa-Nozawa A,Toh H,Yamada S,Nakagawa I
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Wed Sep 18 00:00:00 UTC 2019
TRIM50 regulates Beclin 1 proautophagic activity.
Biochimica et biophysica acta. Molecular cell research
Fusco C,Mandriani B,Di Rienzo M,Micale L,Malerba N,Cocciadiferro D,Sjøttem E,Augello B,Squeo GM,Pellico MT,Jain A,Johansen T,Fimia GM,Merla G
38-2100 was used in Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to expand the roles of TRIMs in regulating selective autophagy, revealing an acetylation-ubiquitination dependent control for autophagy modulation.
Fri Jun 01 00:00:00 UTC 2018
MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy.
Autophagy
Ma X,Zhang S,He L,Rong Y,Brier LW,Sun Q,Liu R,Fan W,Chen S,Yue Z,Kim J,Guan KL,Li D,Zhong Q
38-2100 was used in Western blotting following immunoprecipitation to identify NRBF2 as a critical molecular switch of phosphatidylinositol 3-kinase and autophagy activation, and its on/off state is precisely controlled by MTORC1 through phosphorylation.
Sat Mar 04 00:00:00 UTC 2017
Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin.
Biology open
Marcassa E,Raimondi M,Anwar T,Eskelinen EL,Myers MP,Triolo G,Schneider C,Demarchi F
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Mon May 15 00:00:00 UTC 2017
Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy.
Cell death & disease
Cui D,Sun D,Wang X,Yi L,Kulikowicz E,Reyes M,Zhu J,Yang ZJ,Jiang W,Koehler RC
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Thu Jul 13 00:00:00 UTC 2017
SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.
Autophagy
Wei ZB,Yuan YF,Jaouen F,Ma MS,Hao CJ,Zhang Z,Chen Q,Yuan Z,Yu L,Beurrier C,Li W
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Sat Jul 02 00:00:00 UTC 2016
SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation.
Autophagy
Wei ZB,Yuan YF,Jaouen F,Ma MS,Hao CJ,Zhang Z,Chen Q,Yuan Z,Yu L,Beurrier C,Li W
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Sat Jul 02 00:00:00 UTC 2016
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Nature cell biology
Kaushik S,Cuervo AM
38-2100 was used in immunocytochemistry to use of chaperone-mediated autophagy to facilitate lipolysis by degradation of lipid droplet-associated proteins
Mon Jun 01 00:00:00 UTC 2015
Phosphatidylinositol 3-kinase signaling determines kidney size.
The Journal of clinical investigation
Chen JK,Nagai K,Chen J,Plieth D,Hino M,Xu J,Sha F,Ikizler TA,Quarles CC,Threadgill DW,Neilson EG,Harris RC
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Mon Jun 01 00:00:00 UTC 2015
Phosphatidylinositol 3-kinase signaling determines kidney size.
The Journal of clinical investigation
Chen JK,Nagai K,Chen J,Plieth D,Hino M,Xu J,Sha F,Ikizler TA,Quarles CC,Threadgill DW,Neilson EG,Harris RC
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Mon Jun 01 00:00:00 UTC 2015
GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3.
Autophagy
Zhang D,Zhang W,Li D,Fu M,Chen R,Zhan Q
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Mon Oct 31 00:00:00 UTC 2016
GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3.
Autophagy
Zhang D,Zhang W,Li D,Fu M,Chen R,Zhan Q
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Mon Oct 31 00:00:00 UTC 2016
Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.
Nature communications
Moreau K,Ghislat G,Hochfeld W,Renna M,Zavodszky E,Runwal G,Puri C,Lee S,Siddiqi F,Menzies FM,Ravikumar B,Rubinsztein DC
38-2100 was used in western blot to determine how starvation-induced autophagy is promoted by transcriptional regulation of Annexin A2
Thu Aug 20 00:00:00 UTC 2015
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Thu May 01 00:00:00 UTC 2014
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Thu May 01 00:00:00 UTC 2014
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Thu May 01 00:00:00 UTC 2014
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Thu May 01 00:00:00 UTC 2014
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Thu May 01 00:00:00 UTC 2014
Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.
Autophagy
Sarkar C,Zhao Z,Aungst S,Sabirzhanov B,Faden AI,Lipinski MM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Tue Dec 08 00:00:00 UTC 2015
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.
Nature communications
Lu J,He L,Behrends C,Araki M,Araki K,Jun Wang Q,Catanzaro JM,Friedman SL,Zong WX,Fiel MI,Li M,Yue Z
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunoprecipitation
Thu May 22 00:00:00 UTC 2014
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.
Nature communications
Lu J,He L,Behrends C,Araki M,Araki K,Jun Wang Q,Catanzaro JM,Friedman SL,Zong WX,Fiel MI,Li M,Yue Z
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunoprecipitation
Thu May 22 00:00:00 UTC 2014
Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine.
Gut pathogens
Wu S,Yuan L,Zhang Y,Liu F,Li G,Wen K,Kocher J,Yang X,Sun J
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Wed Aug 07 00:00:00 UTC 2013
Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine.
Gut pathogens
Wu S,Yuan L,Zhang Y,Liu F,Li G,Wen K,Kocher J,Yang X,Sun J
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Wed Aug 07 00:00:00 UTC 2013
Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine.
Gut pathogens
Wu S,Yuan L,Zhang Y,Liu F,Li G,Wen K,Kocher J,Yang X,Sun J
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Wed Aug 07 00:00:00 UTC 2013
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.
Cell
Bodemann BO,Orvedahl A,Cheng T,Ram RR,Ou YH,Formstecher E,Maiti M,Hazelett CC,Wauson EM,Balakireva M,Camonis JH,Yeaman C,Levine B,White MA
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Western Blot
Fri Jan 21 00:00:00 UTC 2011
Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.
Journal of virology
Su WC,Chao TC,Huang YL,Weng SC,Jeng KS,Lai MM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Sat Oct 01 00:00:00 UTC 2011
Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.
Journal of virology
Su WC,Chao TC,Huang YL,Weng SC,Jeng KS,Lai MM
Published figure using VPS34 polyclonal antibody (Product # 38-2100) in Immunofluorescence
Sat Oct 01 00:00:00 UTC 2011
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.
Nature immunology
Berger SB,Romero X,Ma C,Wang G,Faubion WA,Liao G,Compeer E,Keszei M,Rameh L,Wang N,Boes M,Regueiro JR,Reinecker HC,Terhorst C
38-2100 was used in immunoprecipitation to report that SLAM is a microbial sensor aids in the killing of gram-negative bacteria by macrophages
Fri Oct 01 00:00:00 UTC 2010
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
PloS one
Jaeger PA,Pickford F,Sun CH,Lucin KM,Masliah E,Wyss-Coray T
38-2100 was used in western blot to elucidate how Beclin 1 contributes to Alzheimer Disease
Tue Jun 15 00:00:00 UTC 2010
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
PloS one
Jaeger PA,Pickford F,Sun CH,Lucin KM,Masliah E,Wyss-Coray T
38-2100 was used in western blot to elucidate how Beclin 1 contributes to Alzheimer Disease
Tue Jun 15 00:00:00 UTC 2010
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
PloS one
Jaeger PA,Pickford F,Sun CH,Lucin KM,Masliah E,Wyss-Coray T
38-2100 was used in western blot to elucidate how Beclin 1 contributes to Alzheimer Disease
Tue Jun 15 00:00:00 UTC 2010
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
PloS one
Jaeger PA,Pickford F,Sun CH,Lucin KM,Masliah E,Wyss-Coray T
38-2100 was used in western blot to elucidate how Beclin 1 contributes to Alzheimer Disease
Tue Jun 15 00:00:00 UTC 2010
Regulation of amyloid precursor protein processing by the Beclin 1 complex.
PloS one
Jaeger PA,Pickford F,Sun CH,Lucin KM,Masliah E,Wyss-Coray T
38-2100 was used in western blot to elucidate how Beclin 1 contributes to Alzheimer Disease
Tue Jun 15 00:00:00 UTC 2010
Autophagy induction by the pathogen receptor CD46.
Cell host & microbe
Joubert PE,Meiffren G,Grégoire IP,Pontini G,Richetta C,Flacher M,Azocar O,Vidalain PO,Vidal M,Lotteau V,Codogno P,Rabourdin-Combe C,Faure M
Thu Oct 22 00:00:00 UTC 2009
Autophagy induction by the pathogen receptor CD46.
Cell host & microbe
Joubert PE,Meiffren G,Grégoire IP,Pontini G,Richetta C,Flacher M,Azocar O,Vidalain PO,Vidal M,Lotteau V,Codogno P,Rabourdin-Combe C,Faure M
Thu Oct 22 00:00:00 UTC 2009
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.
Blood
Anderson KE,Boyle KB,Davidson K,Chessa TA,Kulkarni S,Jarvis GE,Sindrilaru A,Scharffetter-Kochanek K,Rausch O,Stephens LR,Hawkins PT
38-2100 was used in western blot to assess the role of PI3K signaling pathways in the regulation of the oxidase during phagocytosis of bacteria
Mon Dec 15 00:00:00 UTC 2008
Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?
Translational oncology
Miselli F,Negri T,Gronchi A,Losa M,Conca E,Brich S,Fumagalli E,Fiore M,Casali PG,Pierotti MA,Tamborini E,Pilotti S
38-2100 was used in Western Blotting to support the idea that gastrointestinal stromal tumours activate autophagy rather than apoptosis in response to imatinib treatment and that their molecular makeup includes fingerprints of autophagy.
Mon Dec 01 00:00:00 UTC 2008
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
Proceedings of the National Academy of Sciences of the United States of America
Nobukuni T,Joaquin M,Roccio M,Dann SG,Kim SY,Gulati P,Byfield MP,Backer JM,Natt F,Bos JL,Zwartkruis FJ,Thomas G
Tue Oct 04 00:00:00 UTC 2005
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
Proceedings of the National Academy of Sciences of the United States of America
Nobukuni T,Joaquin M,Roccio M,Dann SG,Kim SY,Gulati P,Byfield MP,Backer JM,Natt F,Bos JL,Zwartkruis FJ,Thomas G
Tue Oct 04 00:00:00 UTC 2005
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
Proceedings of the National Academy of Sciences of the United States of America
Nobukuni T,Joaquin M,Roccio M,Dann SG,Kim SY,Gulati P,Byfield MP,Backer JM,Natt F,Bos JL,Zwartkruis FJ,Thomas G
Tue Oct 04 00:00:00 UTC 2005
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
Proceedings of the National Academy of Sciences of the United States of America
Nobukuni T,Joaquin M,Roccio M,Dann SG,Kim SY,Gulati P,Byfield MP,Backer JM,Natt F,Bos JL,Zwartkruis FJ,Thomas G
Tue Oct 04 00:00:00 UTC 2005
