Exalpha

Vesicle Associated Membrane Protein (VAMP 1/2) Polyclonal Antibody

Name: Vesicle Associated Membrane Protein (VAMP 1\/2) Polyclonal Antibody
Brand: Exalpha
SKU: K105P

查看其他3个VAMP1/VAMP2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

K105P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Human, Rat

宿主/亚型

Sheep / IgG

分类

Polyclonal

类型

Antibody

抗原

Full length VAMP1/2 protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-2 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

PBS

内含物

0.08% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Precautions should be taken upon storage for longer periods. Problems of long term stability may occur with highly diluted solutions. No other preservative agent has been added to the present formulation. For long storage purposes in solution the addition of sodium azide at 0.02 % is advised with the appropriate precautions of use.

The antibody may be used in ELISA and IAC. Depending on conjugate: dilution 1/75,000. (The titer is defined as the dilution that gives 50 % of the absorbance from the maximum absorbance when tested with ELISA). Suggested concentration to use in ELISA: 1/75,000 from the delivered solution. Plates are coated with 400 ng/mL BSA-conjugated C6-alkylphenol. HRP-conjugated anti-rabbit IgG as a tracer 1/8,000

靶标信息

Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: synaptobrevin 1; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); Synaptobrevin-1; Synaptobrevin-2; VAMP-1; VAMP-2; Vesicle-associated membrane protein (synaptobrevin 2); Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1); Vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)

查看更多收起

基因别名: RATVAMPB; RATVAMPIR; SPAX1; SYB; SYB1; SYB2; VAMP-1; VAMP-2; VAMP1; VAMP2