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Proteintech
WBSCR16 Polyclonal Antibody
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产品信息
13796-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
WBSCR16 Fusion Protein Ag4619 (1-350 aa encoded by BC032712)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MALVALVAG ARLGRRLSGP GLGRGHWTAA GRSRSRREAA EAEAEVPVVQ YVGERAARAD RVFVWGFSFS GALGVPSFVV PSSGPGPRAG ARPRRRIQPV PYRLELDQKI SSAACGYGFT LLSSKTADVT KVWGMGLNKD SQLGFHRSRK DKTRGYEYVL EPSPVSLPLD RPQETRVLQV SCGRAHSLVL TDREGVFSMG NNSYGQCGRK VVENEIYSES HRVHRMQDFD GQVVQVACGQ DHSLFLTDKG EVYSCGWGAD GQTGLGHYNI TSSPTKLGGD LAGVNVIQVA TYGDCCLAVS ADGGLFGWGN SEYLQLASVT DSTQVNVPRC LHFSGVGKVR QAACGGTGCA V (1-350 aa encoded by BC032712)
靶标信息
Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: RCC1-like G exchanging factor-like protein; RCC1-like protein; Williams-Beuren syndrome chromosomal region 16 protein; Williams-Beuren syndrome chromosome region 16
基因别名: RCC1L; WBSCR16
UniProt ID: (Human) Q96I51
Entrez Gene ID: (Human) 81554
