Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
WDR24 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
20778-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
WDR24 Fusion Protein Ag14774 (570-920 aa encoded by BC008025)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LGRNQVAQT WTMLRIIYCS PGLVPTANLN HSVGKGGSCG LPLMNSFNLK DMAPGLGSET RLDRSKGDAR SDTVLLDSSA TLITNEDNEE TEGSDVPADY LLGDVEGEED ELYLLDPEHA HPEDPECVLP QEAFPLRHEI VDTPPGPEHL QDKADSPHVS GSEADVASLA PVDSSFSLLS VSHALYDSRL PPDFFGVLVR DMLHFYAEQG DVQMAVSVLI VLGERVRKDI DEQTQEHWYT SYIDLLQRFR LWNVSNEVVK LSTSRAVSCL NQASTTLHVN CSHCKRPMSS RGWVCDRCHR CASMCAVCHH VVKGLFVWCQ GCSHGGHLQH IMKWLEGSSH CPAGCGHLCE YS (570-920 aa encoded by BC008025)
靶标信息
WDR24, as a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. WDR24 is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GATOR2 complex protein WDR24; WD repeat-containing protein 24
基因别名: BC037651; C16orf21; JFP7; WDR24
UniProt ID: (Human) Q96S15, (Mouse) Q8CFJ9
Entrez Gene ID: (Human) 84219, (Mouse) 268933
