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Fabgennix
WDR5 Polyclonal Antibody
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产品信息
WDR5-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Dog,
Chicken,
Human,
Mouse,
Non-human primate,
Plant,
Pig,
Rat,
Xenopus,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide:DVKTGKCLKTLPAHSDPVcorresponding to amino acids 157-174 of Human WDR5 protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3, Set1c WD40 repeat protein, homolog; WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3
基因别名: 2410008O07Rik; AA408785; AA960360; Big; BIG-3; BIG3; CFAP89; SWD3; WDR5; wu:fk47f04; zgc:56591; zgc:76895
UniProt ID: (Bovine) Q2KIG2, (Human) P61964, (Mouse) P61965, (Rat) Q498M4
Entrez Gene ID: (Bovine) 100125836, (Human) 11091, (Pig) 100156729, (Dog) 608113, (Chicken) 417144, (Mouse) 140858, (Rat) 362093, (Zebrafish) 406372
methylated histone binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K16 specific)
protein binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
histone binding
skeletal system development
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
neuron projection development
positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
histone H3 acetylation
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
histone H3-K4 methylation
histone lysine methylation
