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Invitrogen
WDR5 Recombinant Rabbit Monoclonal Antibody (9H25L13)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 5
WDR5 Antibody (703745) in ICC/IF
For immunofluorescence analysis, HCT 116 cells were fixed and permeabilized for detection of endogenous WDR5 using Anti-WDR5 Recombinant Rabbit Monoclonal Antibody (Product # 703475, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731, 1:2000). Panel a) shows representative cells that were stained for detection and localization of WDR5 protein (green), Panel b) is stained for nuclei (blue) using ProLong™ Diamond Antifade Mountant with DAPI (Product # P... View More
产品信息
703745
产品规格
种属反应
Rat,
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9H25L13
抗原
Protein corresponding to human WDR5 [aa1-aa121]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2848236
产品详细信息
This antibody is predicted to react with Mouse, Bovine
靶标信息
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5
基因别名: BIG-3; BIG3; CFAP89; SWD3; WDR5
UniProt ID: (Human) P61964, (Rat) Q498M4
Entrez Gene ID: (Human) 11091, (Rat) 362093
skeletal system development
transcription, DNA-templated
neuron projection development
histone lysine methylation
positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
histone H3 acetylation
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
histone H3-K4 methylation
