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Bethyl Laboratories
WIPI2 Polyclonal Antibody
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WIPI2 Antibody (A305-324A-M) in WB
Detection of human and mouse WIPI2 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-WIPI2 antibody A305-324A-M (lot A305-324A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 10 seconds.
产品信息
A305-324A-M
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 404 to 454 of Human WD repeat domain phosphoinositide-interacting protein 2.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4°C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat and Chicken
靶标信息
WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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