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Abnova
WNT3 Polyclonal Antibody, MaxPab™
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WNT3 Antibody (H00007473-D01P) in WB
Western Blot analysis of WNT3 expression in transfected 293T cell line (H00007473-T01) by WNT3 MaxPab polyclonal antibody.
Lane 1: WNT3 transfected lysate(39.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: WNT3 transfected lysate(39.60 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00007473-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
WNT3 (NP_110380.1, 1 a.a. approximately 355 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEPHLLGLLL GLLLGGTRVL AGYPIWWSLA LGQQYTSLGS QPLLCGSIPG LVPKQLRFCR NYIEIMPSVA EGVKLGIQEC QHQFRGRRWN CTTIDDSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGTSTICG CDSHHKGPPG EGWKWGGCSE DADFGVLVSR EFADARENRP DARSAMNKHN NEAGRTTILD HMHLKCKCHG LSGSCEVKTC WWAQPDFRAI GDFLKDKYDS ASEMVVEKHR ESRGWVETLR AKYSLFKPPT ERDLVYYENS PNFCEPNPET GSFGTRDRTC NVTSHGIDGC DLLCCGRGHN TRTEKRKEKC HCIFHWCCYV SCQECIRIYD VHTCK
靶标信息
WNT3, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4 homolog; Proto-oncogene Wnt-3; wingless-type MMTV integration site family member 3; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
基因别名: INT4; TETAMS; WNT3
UniProt ID: (Human) P56703
Entrez Gene ID: (Human) 7473
cell morphogenesis
mesoderm formation
gamete generation
axon guidance
anterior/posterior axis specification
dorsal/ventral axis specification
positive regulation of gene expression
Wnt signaling pathway
positive regulation of Wnt signaling pathway
neuron differentiation
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
cell fate commitment
positive regulation of collateral sprouting in absence of injury
negative regulation of axon extension involved in axon guidance
Spemann organizer formation at the anterior end of the primitive streak
canonical Wnt signaling pathway
limb bud formation
head morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
