Abnova

WNT3A Polyclonal Antibody, MaxPab™

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问题与答案

问题与答案

抗体检测数据 (3)

WNT3A Antibody in Immunocytochemistry (ICC/IF)

WNT3A Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 3

WNT3A Antibody (H00089780-B01P) in ICC/IF

Immunofluorescence of purified MaxPab antibody to WNT3A on HeLa cell. Antibody concentration is 10 µg/mL.

WNT3A Antibody in Immunocytochemistry (ICC/IF)

WNT3A Antibody in Western Blot (WB)

WNT3A Antibody in Western Blot (WB)

Product Image Gallery

WNT3A Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence of purified MaxPab antibody to WNT3A on HeLa cell. Antibody concentration is 10 µg/mL.

WNT3A Antibody in Western Blot (WB) — Western Blot analysis of WNT3A expression in transfected 293T cell line (H00089780-T01) by WNT3A MaxPab polyclonal antibody.

Lane 1: WNT3A transfected lysate(42.35 KDa).
Lane 2: Non-transfected lysate.

WNT3A Antibody in Western Blot (WB) — WNT3A MaxPab polyclonal antibody. Western Blot analysis of WNT3A expression in human pancreas.

产品信息

H00089780-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

免疫细胞化学 (ICC/IF)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

WNT3A (AAI03922, 1 a.a. approximately 385 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MAPLGYFLLL CSLKQALGSY PIWWSLAVGP QYSSLGSQPI LCASIPGLVP KQLRFCRNYV EIMPSVAEGI KIGIQECQHQ FRGRRWNCTT VHDSLAIFGP VLDKATRESA FVHAIASAGV AFAVTRSCAE GTAAICGCSS RHQGSPGKGW KWGGCSEDIE FGGMVSREFA DARENRPDAR SAMNRHNNEA GRQAIASHMH LKCKCHGLSG SCEVKTCWWS QPDFRAIGDF LKDKYDSASE MVVEKHRESR GWVETLRPRY TYFKVPTERD LVYYEASPNF CEPNPETGSF GTRDRTCNVS SHGIDGCDLL CCGRGHNARA ERRREKCRCV FHWCCYVSCQ ECTRVYDVHT CKNPGSRAGN SAHQPPHPQP PVRFHPPLRR AGKVP

靶标信息

Wnt3a, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: MGC119418; MGC119419; MGC119420; Protein Wnt-3a; wingless-type MMTV integration site family member 3A; wingless-type MMTV integration site family, member 3A; Wnt 3a; WNT3A protein

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基因别名: WNT3A

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UniProt ID: (Human) P56704

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Entrez Gene ID: (Human) 89780

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transcription coactivator activity receptor binding frizzled binding frizzled-2 binding protein binding protein domain specific binding co-receptor binding receptor agonist activity intercellular signal molecule

osteoblast differentiation in utero embryonic development positive regulation of cytokine production positive regulation of protein phosphorylation heart looping positive regulation of receptor internalization negative regulation of heart induction by canonical Wnt signaling pathway axon guidance synapse assembly positive regulation of cell proliferation COP9 signalosome assembly negative regulation of neuron projection development Wnt signaling pathway spinal cord association neuron differentiation hippocampus development cell proliferation in forebrain Wnt signaling pathway involved in forebrain neuroblast division dorsal/ventral neural tube patterning hemopoiesis neuron differentiation extracellular matrix organization mammary gland development positive regulation of B cell proliferation positive regulation of protein binding positive regulation of peptidyl-serine phosphorylation cell proliferation in midbrain cellular protein localization positive regulation of catenin import into nucleus skeletal muscle cell differentiation post-anal tail morphogenesis synaptic vesicle recycling inner ear morphogenesis positive regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of fat cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of mesodermal cell fate specification paraxial mesodermal cell fate commitment positive regulation of skeletal muscle tissue development positive regulation of collateral sprouting in absence of injury negative regulation of axon extension involved in axon guidance negative regulation of neurogenesis positive regulation of sequence-specific DNA binding transcription factor activity palate development canonical Wnt signaling pathway positive regulation of protein tyrosine kinase activity positive regulation of dermatome development canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment regulation of microtubule cytoskeleton organization platelet aggregation cellular response to retinoic acid axis elongation involved in somitogenesis positive regulation of canonical Wnt signaling pathway positive regulation of protein localization to plasma membrane negative regulation of dopaminergic neuron differentiation beta-catenin destruction complex disassembly Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation positive regulation of cell-cell adhesion mediated by cadherin positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation positive regulation of neural precursor cell proliferation positive regulation of hepatocyte proliferation positive regulation of transcription regulatory region DNA binding positive regulation of cardiac muscle cell differentiation