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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • WNT3A Antibodies

          Abnova

          WNT3A Polyclonal Antibody, MaxPab™

          查看其他15个WNT3A抗体
          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
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          Cite WNT3A Polyclonal Antibody, MaxPab™

          • 抗体检测数据 (3)
          WNT3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          WNT3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 3

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          WNT3A Antibody (H00089780-B01P) in ICC/IF

          Immunofluorescence of purified MaxPab antibody to WNT3A on HeLa cell. Antibody concentration is 10 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          WNT3A Antibody in Immunocytochemistry (ICC/IF)
          WNT3A Antibody in Western Blot (WB)
          WNT3A Antibody in Western Blot (WB)

          产品信息

          H00089780-B01P

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500-1:1,000
          -

          免疫细胞化学 (ICC/IF)

          10 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          WNT3A (AAI03922, 1 a.a. approximately 385 a.a) full-length human protein.

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          See Label

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          产品详细信息

          Sequence of this protein is as follows: MAPLGYFLLL CSLKQALGSY PIWWSLAVGP QYSSLGSQPI LCASIPGLVP KQLRFCRNYV EIMPSVAEGI KIGIQECQHQ FRGRRWNCTT VHDSLAIFGP VLDKATRESA FVHAIASAGV AFAVTRSCAE GTAAICGCSS RHQGSPGKGW KWGGCSEDIE FGGMVSREFA DARENRPDAR SAMNRHNNEA GRQAIASHMH LKCKCHGLSG SCEVKTCWWS QPDFRAIGDF LKDKYDSASE MVVEKHRESR GWVETLRPRY TYFKVPTERD LVYYEASPNF CEPNPETGSF GTRDRTCNVS SHGIDGCDLL CCGRGHNARA ERRREKCRCV FHWCCYVSCQ ECTRVYDVHT CKNPGSRAGN SAHQPPHPQP PVRFHPPLRR AGKVP

          靶标信息

          Wnt3a, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: MGC119418; MGC119419; MGC119420; Protein Wnt-3a; wingless-type MMTV integration site family member 3A; wingless-type MMTV integration site family, member 3A; Wnt 3a; WNT3A protein

          查看更多 收起

          基因别名: WNT3A

          查看更多 收起

          UniProt ID: (Human) P56704

          查看更多 收起

          Entrez Gene ID: (Human) 89780

          查看更多 收起

          功能
          transcription coactivator activity receptor binding frizzled binding frizzled-2 binding protein binding protein domain specific binding co-receptor binding receptor agonist activity intercellular signal molecule
          参与通路
          osteoblast differentiation in utero embryonic development positive regulation of cytokine production positive regulation of protein phosphorylation heart looping positive regulation of receptor internalization negative regulation of heart induction by canonical Wnt signaling pathway axon guidance synapse assembly positive regulation of cell proliferation COP9 signalosome assembly negative regulation of neuron projection development Wnt signaling pathway spinal cord association neuron differentiation hippocampus development cell proliferation in forebrain Wnt signaling pathway involved in forebrain neuroblast division dorsal/ventral neural tube patterning hemopoiesis neuron differentiation extracellular matrix organization mammary gland development positive regulation of B cell proliferation positive regulation of protein binding positive regulation of peptidyl-serine phosphorylation cell proliferation in midbrain cellular protein localization positive regulation of catenin import into nucleus skeletal muscle cell differentiation post-anal tail morphogenesis synaptic vesicle recycling inner ear morphogenesis positive regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of fat cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of mesodermal cell fate specification paraxial mesodermal cell fate commitment positive regulation of skeletal muscle tissue development positive regulation of collateral sprouting in absence of injury negative regulation of axon extension involved in axon guidance negative regulation of neurogenesis positive regulation of sequence-specific DNA binding transcription factor activity palate development canonical Wnt signaling pathway positive regulation of protein tyrosine kinase activity positive regulation of dermatome development canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment regulation of microtubule cytoskeleton organization platelet aggregation cellular response to retinoic acid axis elongation involved in somitogenesis positive regulation of canonical Wnt signaling pathway positive regulation of protein localization to plasma membrane negative regulation of dopaminergic neuron differentiation beta-catenin destruction complex disassembly Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation positive regulation of cell-cell adhesion mediated by cadherin positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation positive regulation of neural precursor cell proliferation positive regulation of hepatocyte proliferation positive regulation of transcription regulatory region DNA binding positive regulation of cardiac muscle cell differentiation
          It has to be done as per old AB suggested Products section.
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