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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • WNT5A Antibodies

          Invitrogen

          WNT5A Polyclonal Antibody

          1 篇参考文献
          查看其他19个WNT5A抗体

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          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
          技术支持

          Cite WNT5A Polyclonal Antibody

          • 抗体检测数据 (6)
          WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 6

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          WNT5A Antibody (PA5-72454) in IHC (P)

          Immunohistochemistry analysis of WNT5A in paraffin-embedded Human thyroid carcinoma tissue. Samples were incubated with WNT5A polyclonal antibody (Product # PA5-72454) using a dilution of 1:100 for 1 hour at room temperature followed by an undiluted biotinylated CRF Anti-Polyvalent HRP Polymer antibody. Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a ED... View More {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WNT5A Antibody in Western Blot (WB)
          WNT5A Antibody in Western Blot (WB)
          WNT5A Antibody in Flow Cytometry (Flow)
          WNT5A Antibody in Flow Cytometry (Flow)

          产品信息

          PA5-72454

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:500
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:100
          -

          免疫细胞化学 (ICC/IF)

          -
          查看1篇已发表文章 1篇已发表文章

          流式细胞分析 (Flow)

          1:25
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          已发表种属

          Human

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human WNT5A
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.5 mg/mL

          纯化类型

          Protein A, Antigen affinity chromatography

          保存液

          PBS, pH 7.4

          内含物

          0.09% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2718308

          靶标信息

          Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: OTTHUMP00000212837; OTTHUMP00000212861; Protein Wnt-5a; wingless-related MMTV integration site 5A; wingless-type MMTV integration site 5A; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein

          查看更多 收起

          基因别名: 8030457G12Rik; hWNT5A; Wnt-5a; WNT5A

          查看更多 收起

          UniProt ID: (Human) P41221, (Mouse) P22725

          查看更多 收起

          Entrez Gene ID: (Human) 7474, (Rat) 64566, (Mouse) 22418

          查看更多 收起

          功能
          transcription factor activity, sequence-specific DNA binding frizzled binding frizzled-2 binding receptor tyrosine kinase-like orphan receptor binding cytokine activity protein binding protein domain specific binding transcription regulatory region DNA binding receptor agonist activity chemoattractant activity involved in axon guidance molecular_function receptor binding intercellular signal molecule
          参与通路
          activation of MAPK activity establishment of planar polarity somitogenesis epithelial to mesenchymal transition positive regulation of endothelial cell proliferation heart looping positive regulation of mesenchymal cell proliferation lens development in camera-type eye positive regulation of cytokine secretion involved in immune response type B pancreatic cell development planar cell polarity pathway involved in axis elongation optic cup formation involved in camera-type eye development Wnt signaling pathway, calcium modulating pathway activation of JUN kinase activity axon guidance synapse assembly hindgut morphogenesis midgut development male gonad development anterior/posterior axis specification, embryo response to organic substance positive regulation of endothelial cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of T cell chemotaxis positive regulation of neuron projection development Wnt signaling pathway olfactory bulb interneuron development neuron differentiation keratinocyte differentiation negative regulation of BMP signaling pathway positive regulation of cGMP metabolic process prostate gland development positive regulation of protein binding activation of protein kinase B activity response to estradiol positive regulation of interferon-gamma production positive regulation of interleukin-6 production positive regulation of peptidyl-serine phosphorylation response to testosterone cellular protein localization non-canonical Wnt signaling pathway post-anal tail morphogenesis chemoattraction of serotonergic neuron axon chemorepulsion of dopaminergic neuron axon non-canonical Wnt signaling pathway via JNK cascade negative regulation of fibroblast growth factor receptor signaling pathway wound healing embryonic digit morphogenesis positive regulation of macrophage activation negative regulation of apoptotic process estrous cycle positive regulation of chemokine biosynthetic process cell fate commitment establishment of epithelial cell apical/basal polarity negative regulation of fat cell differentiation positive regulation of protein catabolic process positive regulation of angiogenesis positive regulation of ossification positive regulation of endocytosis positive regulation of meiotic nuclear division negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter negative regulation of melanin biosynthetic process positive regulation of fibroblast proliferation lung alveolus development paraxial mesoderm formation notochord morphogenesis embryonic skeletal system development genitalia development negative regulation of axon extension involved in axon guidance hypophysis morphogenesis negative regulation of epithelial cell proliferation positive regulation of interleukin-1 beta secretion positive regulation of inflammatory response positive regulation of NF-kappaB transcription factor activity cartilage development response to glucocorticoid negative regulation of synapse assembly response to hyperoxia palate development convergent extension involved in axis elongation convergent extension involved in organogenesis uterus development cervix development vagina development canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway urinary bladder development face development positive regulation of type I interferon-mediated signaling pathway lateral sprouting involved in mammary gland duct morphogenesis mesenchymal-epithelial cell signaling negative regulation of prostatic bud formation mammary gland branching involved in thelarche epithelial cell proliferation involved in mammary gland duct elongation positive regulation of response to cytokine stimulus regulation of branching involved in mammary gland duct morphogenesis planar cell polarity pathway involved in gastrula mediolateral intercalation mesodermal to mesenchymal transition involved in gastrulation positive regulation of macrophage cytokine production positive regulation of cartilage development planar cell polarity pathway involved in outflow tract morphogenesis planar cell polarity pathway involved in ventricular septum morphogenesis planar cell polarity pathway involved in cardiac right atrium morphogenesis planar cell polarity pathway involved in cardiac muscle tissue morphogenesis planar cell polarity pathway involved in pericardium morphogenesis positive regulation of thymocyte apoptotic process cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to interferon-gamma hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of mesenchymal cell proliferation primitive streak formation positive regulation of protein kinase C signaling negative regulation of canonical Wnt signaling pathway cochlea morphogenesis planar cell polarity pathway involved in neural tube closure activation of GTPase activity melanocyte proliferation positive regulation of protein kinase C activity positive regulation of protein localization to synapse regulation of cellular protein localization excitatory synapse assembly inhibitory synapse assembly negative regulation of cell proliferation in midbrain Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation positive regulation of cell-cell adhesion mediated by cadherin positive regulation of non-canonical Wnt signaling pathway positive regulation of interleukin-8 secretion ameboidal-type cell migration positive regulation of cytokine production neural tube closure positive regulation of protein phosphorylation morphogenesis of an epithelium pericardium morphogenesis axis elongation protein phosphorylation JNK cascade determination of left/right symmetry positive regulation of cell proliferation anterior/posterior pattern specification response to organic cyclic compound cell migration neural tube development positive regulation of cell-cell adhesion cell differentiation lung development embryonic limb morphogenesis regulation of protein localization limb morphogenesis inner ear morphogenesis positive regulation of JUN kinase activity positive regulation of JNK cascade development of primary male sexual characteristics digestive tract morphogenesis neuron projection morphogenesis positive regulation of epithelial cell proliferation negative chemotaxis convergent extension tube closure cellular response to molecule of bacterial origin dopaminergic neuron differentiation signal transduction cell-cell signaling multicellular organism development embryo development organ morphogenesis
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