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Proteintech
WWP2 Polyclonal Antibody
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产品信息
12197-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
WWP2 Fusion Protein Ag2835 (1-355 aa encoded by BC013645)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MASASSSRA GVALPFEKSQ LTLKVVSAKP KVHNRQPRIN SYVEVAVDGL PSETKKTGKR IGSSELLWNE IIILNVTAQS HLDLKVWSCH TLRNELLGTA SVNLSNVLKN NGGKMENMQL TLNLQTENKG SVVSGGELTI FLDGPTVDLG NVPNGSALTD GSQLPSRDSS GTAVAPENRH QPPSTNCFGG RSRTHRHSGA SARTTPATGE QSPGARSRHR QPVKNSGHSG LANGTVNDEP TTATDPEEPS VVGVTSPPAA PLSVTPNPNT TSLPAPATPA EGEEPSTSGT QQLPAAAQAP DALPAGWEQR ELPNGRVYYV DHNTKTTTWE RPLPPGWEKR TDPRGRFYYV DHNTRT (1-355 aa encoded by B C013645)
靶标信息
This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AIP2; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; HECT-type E3 ubiquitin transferase WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain-containing protein 2; WW domain-containing protein 4
基因别名: 1300010O06Rik; AA690238; AIP2; AW554328; WWP2; WWp2-like
UniProt ID: (Human) O00308, (Mouse) Q9DBH0
Entrez Gene ID: (Human) 11060, (Rat) 291999, (Mouse) 66894
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
ubiquitin-protein transferase activity
protein binding
transcription factor binding
ligase activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cellular protein modification process
negative regulation of gene expression
protein ubiquitination
negative regulation of transporter activity
regulation of ion transmembrane transport
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
viral entry into host cell
negative regulation of protein transport
protein autoubiquitination
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity
