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Recommended positive controls: 293T, HeLa, HepG2, Raji.
Predicted reactivity: Rhesus Monkey (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ12610; Non-homologous end-joining factor 1; nonhomologous end-joining factor 1; Protein cernunnos; XRCC4-like factor
基因别名: NHEJ1; XLF
UniProt ID: (Human) Q6IA64
Entrez Gene ID: (Human) 79840