Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Immunogen sequence: MEELEQGLLM QPWAWLQLAE NSLLAKVFIT KQGYALLVSD LQQVWHEQVD TSVVSQRAKE LNKRLTAPPA AFLCHLDNLL RPLLKDAAHP SEATFSCDCV ADALILRVRS ELSGLPFYWN FHCMLASPSL VSQHLIRPLM GMSLALQCQV RELATLLHMK DLEIQDYQES GATLIRDRLK TEPFEENSFL EQFMIEKLPE ACSIGDGKPF VMNLQDLYMA VTTQEVQVGQ KHQGAGDPHT SNSASLQGID SQCVNQPEQL VSSAPTLSAP EKESTGTSGP LQRPQLSKVK RKKPRGLFS; Positive Samples: Hela, Jurkat; Cellular Location: Nucleus
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ12610; Non-homologous end-joining factor 1; nonhomologous end-joining factor 1; Protein cernunnos; XRCC4-like factor
基因别名: 1700029B21Rik; cernunnos; NHEJ1; XLF
UniProt ID: (Human) Q9H9Q4, (Mouse) Q3KNJ2, (Rat) Q6AYI4
Entrez Gene ID: (Human) 79840, (Mouse) 75570, (Rat) 363251
