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Invitrogen
Yellow Fever Virus NS4B Polyclonal Antibody
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Yellow Fever Virus NS4B Antibody (PA5-112028) in WB
Western Blot using Yellow Fever Virus NS4B Polyclonal Antibody (Product # PA5-112028). Non-transfected (–) and transfected (+) 293T whole cell extracts (30 µg) were separated by 12% SDS-PAGE, and the membrane was blotted with Yellow Fever Virus NS4B Polyclonal Antibody (Product # PA5-112028) diluted at 1:5,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-112028
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of Yellow Fever Virus NS4B Protein (Yellow fever virus (strain 17D vaccine)). The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.18 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Yellow fever virus (YFV) is an RNA virus belonging to the genus Flavivirus in the family Flaviviridae. YFV measures 40-60 nm in diameter and has a spherical, enveloped structure containing a single-stranded positive-sense RNA genome. The genome encodes three structural proteins (C, prM/M, and E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). YFV is transmitted by Aedes mosquitoes and is endemic in tropical regions of Africa and South America. It causes yellow fever, a hemorrhagic disease characterized by symptoms such as fever, jaundice, hemorrhage, and organ failure. Pathogenesis involves liver infection leading to hepatocyte and Kupffer cell damage, with the virus utilizing specific genes and molecular mechanisms for neurotropism and viscerotropism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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