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Yohimbine is an alkaloid derived primarily from the bark of the African Yohimbe tree (Pausinystalia johimbe), known for its use in treating erectile dysfunction and certain other conditions related to sexual dysfunction. Structurally, it is characterized by an indole alkaloid group that contributes to its pharmacological activity. Yohimbine functions as an alpha-2 adrenergic receptor antagonist, facilitating increased blood flow and sympathetic nervous system activity, which can enhance libido and energy levels. Its pharmacokinetic profile includes rapid absorption and metabolism, primarily through oral administration, often found in dietary supplements. While yohimbine has shown effectiveness in specific therapeutic scenarios, its usage is associated with potential side effects such as increased heart rate, anxiety, and hypertension, necessitating careful monitoring and dosage control. Research efforts continue to evaluate yohimbine's full range of effects and interactions, particularly concerning its role in mental health and weight management.
仅用于科研。不用于诊断过程。未经明确授权不得转售。