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Invitrogen
ZBED3 Polyclonal Antibody
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产品信息
PA5-20733
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide from near the carboxy terminus of human ZBED3.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Wet ice
RRID
产品详细信息
Despite its predicted molecular weight, ZBED3 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is Jurkat cell lysate.
PA5-20733 can be used with blocking peptide PEP-0847.
靶标信息
Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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