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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: MNHQHSTAQL NLSNMKISAE CFDLILQFMY LGKIMTAPSS FEQFKVAMNY LQLYNVPDCL EDIQDADCSS S
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 97%.
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger and BTB domain-containing protein 1
基因别名: KIAA0997; ZBTB1
Entrez Gene ID: (Human) 22890