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Invitrogen
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Immunogen sequence: CLPEQEQRPP LVQQRFLDVA NLNNPCTSTQ EPTEGLGECY HPRCDIFPGI VSKHLETSLT INKCVPVSKC DTTHSSVSCL EMDVPIDLSK KCLSQSERTT TSPKRLLDYH ECTVCKISFN KVENYLAHKQ
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。