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Proteintech
ZFYVE19 Polyclonal Antibody
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产品信息
23163-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZFYVE19 Fusion Protein Ag19593 (123-471 aa encoded by BC015738)
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VCKQCHEVL TRGSSANASK WSPPQNYKKR VAALEAKQKP STSQSQGLTR QDQMIAERLA RLRQENKPKL VPSQAEIEAR LAALKDERQG SIPSTQEMEA RLAALQGRVL PSQTPQPAHH TPDTRTQAQQ TQDLLTQLAA EVAIDESWKG GGPAASLQND LNQGGPGSTN SKRQANWSLE EEKSRLLAEA ALELREENTR QERILALAKR LAMLRGQDPE RVTLQDYRLP DSDDDEDEET AIQRVLQQLT EEAALDEASG FNIPAEQASR PWTQPRGAEP EAQDVDPRPE AEEEELPWCC ICNEDATLRC AGCDGDLFCA RCFREGHDAF ELKEHQTSAY SPPRAGQEH (123-471 aa encoded by BC015738)
靶标信息
Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; Zinc finger FYVE domain-containing protein 19; zinc finger, FYVE domain containing 19
基因别名: ANCHR; MPFYVE; ZFYVE19
UniProt ID: (Human) Q96K21
Entrez Gene ID: (Human) 84936
