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Immunogen sequence: AGRHSVASAQ LQEKLAGAQR QLGQLRAQEA GLQQEQRKAD THKKMTEF
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 93%; Sheep: 93%
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G patch domain-containing protein 6; Zinc finger and G patch domain-containing protein; Zinc finger CCCH domain-containing protein 9; zinc finger CCCH-type with G patch domain; Zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; zinc finger, CCCH-type with G-patch domain
基因别名: GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZGPAT; ZIP
UniProt ID: (Human) Q8N5A5
Entrez Gene ID: (Human) 84619