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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Samples: Rat lung; Cellular Location: Nucleus
Immunogen sequence: PDLSSLQAGS ACLAKHQDGL WHAARITDVD NGYYTVKFDS LLLREAVVEG DGILPPLRTE
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger CCCH-type with G patch domain-containing protein
基因别名: RGD1310801; Zgpat
UniProt ID: (Rat) Q5PPF5
Entrez Gene ID: (Rat) 296478