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Proteintech
ZIC1 Polyclonal Antibody
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产品信息
25004-1-AP
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZIC1 fusion protein Ag13400
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: DFLFRNRGFG DAAAAASAQH SLFAASAGGF GGPHGHTDAA GHLLFPGLHE QAAGHASPNV VNGQMRLGFS GDMYPRPEQY GQVTSPRSEH YAAPQLHGYG PMNVNMAAHH GAGAFFRYMR QPIKQELICK WIEPEQLANP KKSCNKTFST MHELVTHVTV EHVGGPEQSN HICFWEECPR EGKPFKAKYK LVNHIRVHTG EKPFPCPFPG CGKVFARSEN LKIHKRTHTG EKPFKCEFEG CDRRFANSSD RKKHMHVHTS DKPYLCKMCD KSYTHPSSLR KHMKVHESSS QGSQPSPAAS SGYESSTPPT IVSPSTDNPT TSSLSPSSSA VHHTAGHSAL SSNFNEWYV
靶标信息
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1
基因别名: CRS6; ZIC; ZIC1; ZNF201
UniProt ID: (Human) Q15915
Entrez Gene ID: (Human) 7545, (Rat) 64618
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
molecular_function
nucleic acid binding
C2H2 zinc finger transcription factor
transcription from RNA polymerase II promoter
pattern specification process
brain development
adult walking behavior
regulation of smoothened signaling pathway
spinal cord development
cell differentiation
positive regulation of protein import into nucleus
inner ear morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
central nervous system development
biological_process
